Basic assessment on adding platelet measurement to legal health checkup in Japan: A cross-sectional and 20-year longitudinal studyArticle Published on 2023-04-032023-06-13 Journal: Frontiers in Public Health [Category] B형 간염, [키워드] Fatty liver FIB-4 index legal health checkups Platelet count Viral hepatitis. [DOI] 10.3389/fpubh.2023.1106831 PMC 바로가기
PCR-based diagnosis of respiratory virus in postsurgical septic patients: A preliminary study before SARS-CoV-2 pandemic수술 후 패혈증 환자에서 PCR 기반 호흡기 바이러스 진단: SARS-CoV-2 범유행 전 예비 연구Article Published on 2022-08-122022-09-11 Journal: Medicine [Category] SARS, 치료기술, [키워드] 28-day mortality 95% CI adjusted confounding variables determine Diagnosis Factor group groups hospital hypertension ICU ICU admission identify independent Infection intensive care unit Logistic regression analysis lymphocyte Lymphocyte count lymphopenia microbiota Mortality multivariate multivariate logistic regression analysis not significantly different pandemic patients PCR PCR test Platelet Platelet count positive positive PCR result postoperative Prevalence recruited regression analysis respiratory respiratory insufficiency respiratory sample Respiratory samples respiratory tract respiratory virus respiratory virus respiratory viruses SARS-CoV-2 pandemic Sepsis septic septic patient virus virus was used [DOI] 10.1097/MD.0000000000029902 PMC 바로가기 [Article Type] Article
Sputnik-V reactogenicity and immunogenicity in the blood and mucosa: a prospective cohort study혈액 및 점막의 스푸트니크-V 반응원성과 면역원성: 전향적 코호트 연구Article Published on 2022-08-012022-09-11 Journal: Scientific Reports [Category] SARS, 임상, 진단, 치료기술, 치료법, [키워드] adverse event adverse events alteration assays baseline Blood blood platelet collected condition correlated COVID-19 COVID-19 vaccine COVID-19 vaccines detectable diagnostic dose Effect Efficacy Elevation elicited Gam-COVID-Vac growth Heterologous immune immunization immunology injection Kazakhstan Local Mild-to-moderate mucosal nasal Nasopharyngeal swab nasopharyngeal swabs oncogene outcome participant performed Platelet count populations potentially life-threatening proportion prospective cohort study Questionnaires reactogenic reactogenicity reduced regimen regulated reported SARS-CoV-2 SARS-CoV-2 immunity seroconversion rate Serum level serum levels subject systemic adverse event systemic reactions the vaccine vaccination Vaccine vector Virus neutralization while [DOI] 10.1038/s41598-022-17514-3 PMC 바로가기 [Article Type] Article
A Rational Approach to Coagulation TestingReview Published on 2022-07-042023-07-08 Journal: Laboratory medicine [Category] COVID19(2023년), [키워드] activated partial thomboplastin time Coagulation fibrinogen Platelet count Prothrombin time test selection Viscoelastic testing. [DOI] 10.1093/labmed/lmac005 PMC 바로가기 [Article Type] Review
Simultaneous Occurrence of Immune-Mediated Thrombocytopenia and Myocarditis After mRNA-1273 COVID-19 Vaccination: A Case ReportmRNA-1273 COVID-19 예방접종 후 면역매개성 혈소판감소증과 심근염의 동시 발생: 증례보고Case Reports Published on 2022-05-302022-09-11 Journal: Journal of Korean medical science [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 administration Admission assumed Blood blood test cardiac enzyme cardiac enzymes caused chest pain coronavirus COVID-19 discharged Dyspnea emergency department Endomyocardial biopsy expression Immunoglobulin incidence innate immune system Intravenous immunoglobulin marker mechanism Messenger RNA Mild Moderna mRNA mRNA vaccination mRNA-1273 mRNA-1273 vaccine myocarditis occur occurred Patient performed Platelet Platelet count problem report reported severe acute respiratory syndrome Coronavirus Simultaneous Spread sweating thrombocytopenia vaccination vaccination. Vaccine [DOI] 10.3346/jkms.2022.37.e169 PMC 바로가기 [Article Type] Case Reports
Pathogenetic factors fanning the flames of COVID-19 to cause rhino-orbito-cerebral mucormycosis: An observational studyCOVID-19의 불길을 부채질하여 rhino-orbito-cerebral mucormycosis를 일으키는 병원성 요인: 관찰 연구Observational Study Published on 2022-05-012022-09-11 Journal: Journal de mycologie médicale [Category] COVID19(2023년), SARS, 변종, 임상, [키워드] Absolute lymphocyte count absolute neutrophil count age ALC ANC Clinical severity Comorbidities coronavirus disease Coronavirus disease-19 COVID COVID-19 COVID-19 pandemic COVID-19 severity Cytokine storm D-dimer Delta delta variant Delta variants diabete diabetes Diabetic diabetic ketoacidosis element elevated Factor fanning feature ferritin First wave first-wave Gender Hyperferritinemia identify IL-6 incidence interleukin interleukin-6 lymphocyte male males Mucormycosis neutrophil no significant difference pathogenic Pathways Patient Platelet Platelet count renal dysfunction retrospective Rhino-orbito-cerebral mucormycosis. second wave Serum ferritin severe COVID-19 significant difference significantly steroid steroid therapy Steroids therapy treated was done while [DOI] 10.1016/j.mycmed.2022.101252 PMC 바로가기 [Article Type] Observational Study
Platelet and immune signature associated with a rapid response to the BNT162b2 mRNA COVID-19 vaccineBNT162b2 mRNA COVID-19 백신에 대한 신속한 반응과 관련된 혈소판 및 면역 신호Article Published on 2022-04-012022-09-12 Journal: Journal of thrombosis and haemostasis : JTH [Category] COVID19(2023년), SARS, 진단, [키워드] aggregates B cells Biomarker BNT162b2 BNT162b2 mRNA CD31 circulating platelet COVID-19 COVID-19 vaccine Critical cytokine response dose effective Efficacy elevated enrolled eosinophils expressed feature females first dose healthy volunteer humoral identify immune response immune signature immune system Immunity inhibitory leukocyte median motif mounted mRNA-based COVID-19 vaccine mRNA-based vaccine neutralizing antibody non-classical monocyte of BNT162b2 participant Platelet platelet activation Platelet count rapid immune response rapid response reactive receptor responders second dose stability stimulate the vaccine Vaccine Vaccines Vaccines. Vascular [DOI] 10.1111/jth.15648 PMC 바로가기 [Article Type] Article
Humoral Immunogenicity and Reactogenicity of the Standard ChAdOx1 nCoV-19 Vaccination in TaiwanArticle Published on 2022-02-172022-10-28 Journal: Vaccines [Category] COVID-19, [키워드] 95% CI Administered age analyzed anti-RBD Anti-RBD IgG anti-Spike IgG anti-spike IgG level Asian Asian populations body weight boost ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine clinically correlated COVID-19 D-dimer level death declined elicited enrolled fatigue female Fever geometric mean concentration GMC GMCs group Humoral immunity immunogenicity Neutralizing antibody titer Pain participant Platelet Platelet count Population reactogenicity receive recipient recipients response robust SARS-CoV-2 SARS-CoV-2 antibodies Serious Adverse Event seroconversion rate significantly Standard statistically Taiwan vaccination Vaccine [DOI] 10.3390/vaccines10020312 PMC 바로가기 [Article Type] Article
Delta neutrophil index and C-reactive protein: a potential diagnostic marker of multisystem inflammatory syndrome in children (MIS-C) with COVID-19델타 호중구 지수 및 C 반응성 단백질: COVID-19가 있는 어린이(MIS-C)의 다기관 염증 증후군의 잠재적 진단 마커Observational Study Published on 2022-02-012022-09-11 Journal: European journal of pediatrics [Category] MERS, 바이오마커, 임상, [키워드] 113 patient 113 patients Absolute lymphocyte count absolute neutrophil count albumin ALC Analysis ANC C-reactive protein can be used children circulating clinician control group correlation COVID COVID-19 CRP cutoff value Delta Delta neutrophil index determine Diagnosis diagnostic Diagnostic marker DNI elevated evaluate evaluated fraction granulocyte Granulocytes healthy controls Hemogram hyperinflammation immature Infection Inflammation Inflammatory Laboratory life-threatening lymphocyte marker Mild MIS MIS-C moderate multisystem inflammatory syndrome in children. Negative predictive value neutrophil observational study Patient Platelet Platelet count platelet counts Positive predictive value Predictive value reflect retrospective sedimentation sensitivity serum severity sodium specificity statistically significant syndrome were recorded with COVID-19 [DOI] 10.1007/s00431-021-04281-y PMC 바로가기 [Article Type] Observational Study
Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types슈퍼 대화식 프로모터는 혈액 계통 세포 유형에서 세포 유형-특이 적 조절 네트워크에 대한 통찰력을 제공Research Article Published on 2022-01-312022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] analysis Analysis ATAC-seq binding Blood blood cell Blood cells capture CD4 Cell cell type cell types chromatin compendium complex Critical disrupt driven by enhancer enhancers EPHB3 ETS1 explain Express expression level FIVE Follow-up functional Genetic variant GWAS GWAS variant GWAS variants help hematological hypothese identify implication include independent Interaction interactions interactivity Interpretation Lineage locus lymphocyte Lymphocyte count motifs norm overlap Phenotypes PIR Platelet Platelet count promoter promoters provide redundancy Region regions Regulatory regulatory network regulatory region resource strong interactions traits transcription factor transcriptional transcriptional regulation variant variants [DOI] 10.1371/journal.pgen.1009984 PMC 바로가기 [Article Type] Research Article